对于患有脂肪肝的人来说,这是一个好消息: 力量训练可以消除脂肪肝

日期: 2015年7月27日,

来源: 以色列海法大学

简介:

大约30%的人患有脂肪肝,这是西方世界最常见的肝病。这种疾病会导致肝脏炎症和肝硬化。一项新的研究发现,体育锻炼不仅可以帮助减少肝脏脂肪,而且不仅仅是有氧运动。

分享: 完整的故事

健身房的阻力(力量)训练导致肝脏脂肪含量下降。这是海法大学与特拉维夫医学中心和特拉维夫大学合作的一项新研究的发现。海法大学公共卫生学院的Shira zelell - sagi博士进行了这项研究,他说:“对于那些身体受限或活动性较低的患者来说,阻止他们进行有氧运动是一种有效的选择。”

在以往的研究基础上,脂肪肝的定义是脂肪率超过肝脏体积的5- 10%。该病大约影响30%的公众,被认为是西方世界最常见的肝病。过度肥胖,腹部肥胖,糖尿病,血脂异常,特别是甘油三酯会增加脂肪肝的风险,从而导致肝脏炎症和肝硬化。

这种疾病通常是无症状的,尽管患者有时会感到疲劳,与健康的个体相比缺乏活力。Oren Shibolet教授补充说

脂肪肝因代谢并发症如糖尿病、心血管疾病、肝硬化和肝癌的发展而引起发病率和死亡率。由于对该病的药物治疗非常有限或不存在,主要的重点是生活方式的修改。在这方面,我们的研究是少数几个临床试验之一,以显示在减少肝脂肪的阻力训练的好处。根据Zelber-Sagi博士的说法,尽管患有这种疾病的患者认识到身体活动的重要性,但他们往往缺乏参与这种活动的动力,尤其是在有氧运动的情况下,而有氧运动通常是耗时的。

 

 

目前的研究是由海法大学的一组研究人员和由Shira Zelber-Sagi博士、Oren Shibolet教授和Assaf Buch博士领导的特拉维夫医疗中心进行的。研究人员决定研究阻力训练对脂肪肝的影响,这种训练通常比有氧运动更简单、更专注。这项研究包括82名年龄在20-65岁之间的受试者,他们在研究开始前的六个月被诊断为患有脂肪肝。参与者被随机分为一个抵抗训练组和一个被要求进行伸展运动的对照组。研究人员要求参与者在学习期间不要改变他们的身体活动习惯,继续他们的日常饮食,并服用他们的处方药。在研究期间,参与者进行了体重、血压、肝脏酶、血脂、血糖和胰岛素的血液测试。在健身房的阻力训练是根据一种统一的方案来定义的,它的阻力(力量)水平根据病人的能力而调整。这项训练是由阿萨夫·布奇设计的,包括几组不同的耐力练习,包括手臂、胸部和腿部,持续时间为40分钟,每周3次。

在为期三个月的研究结束时,研究人员发现,在体育馆里的阻力训练导致了肝脏脂肪的减少,这是根据研究中所采用的特殊超声检查发现的肝脏脂肪含量。由穆里尔·韦伯医生开发的这项检查可以量化肝脏脂肪。Zelber-Sagi博士解释道:“阻力训练并不是为了显著降低体重,实际上,整体的减肥效果非常轻微。然而,在超声检查中,阻力(力量)训练似乎对肝脏脂肪水平下降有特殊的影响。

研究还发现,体育锻炼导致血液中胆固醇水平显著下降。研究人员说:“我们认为体育锻炼可以提高胰岛素敏感性,从而降低肝脏中的胆固醇水平和血液中的胆固醇水平。”这项研究还首次表明,阻力训练导致血液中铁蛋白水平降低。铁蛋白是一种在肝脏中发现的促进铁储存的蛋白质。然而,高水平的铁蛋白可以显示肝损伤,包括炎症。因此,铁蛋白水平的下降可能反映了肝脏状况的改善。

Shibolet教授总结道:“我们强烈建议脂肪肝患者参与日常的体育锻炼,无论是阻力(力量)训练还是有氧运动,保持健康的饮食和减肥。”

Zilber-Sagi博士总结道:“我们知道减肥和坚持减肥是多么困难。”因此,重要的是找到其他方法,我们可以长期治疗病人,同时使他们维持高质量的生活。无氧(力量)训练就是其中之一。

参考文献

Good news for people suffering from fatty liver disease: Resistance training can help

Date:

July 27, 2015

Source:

University of Haifa

Summary:

Approximately 30% of the population suffer from fatty liver disease, the most common liver disease in the Western world. The disease can lead to inflammation and cirrhosis of the liver. A new study has found that gym training, and not only aerobic exercises, can help reduce liver fat

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FULL STORY

Resistance training in the gym leads to a fall in liver fat levels. This is the finding of a new study held at the University of Haifa in cooperation with Tel Aviv Medical Center and Tel Aviv University. "For patients suffering from physical limitations or low motivation that prevents them performing aerobic exercises, resistance training can be an effective alternative," comments Dr. Shira Zelber-Sagi from the School of Public Health at the University of Haifa, who undertook the study.

On the basis of past studies, fatty liver disease is defined as a fat rate in excess of 5-10 percent of liver volume. The disease affects approximately 30 percent of the public and is considered the commonest liver disease in the Western world. Excessive weight, abdominal obesity, diabetes, dyslipidemia, and in particular triglycerides increase the risk of developing fatty liver disease, which can lead to inflammation and cirrhosis of the liver.

The disease is usually asymptomatic, although patients sometimes report fatigue and a lack of vitality by comparison to healthy individuals. Prof Oren Shibolet adds that "

Fatty liver causes morbidity and mortality due to metabolic complications such as diabetes and cardiovascular disease, the development of cirrhosis and liver cancer. Because drug treatment for the disease is very limited or nonexistent, the main emphasis is on life style modifications. In this aspect our study is one of a few clinical trials to show the benefit of resistance training in reducing liver fat." According to Dr. Zelber-Sagi, although patients with the disease recognize the importance of physical activity, they often lack the motivation to engage in such activity, particularly in the case of aerobic exercises, which are usually time consuming.

The current study was undertaken by a team of researchers from the University of Haifa, and the Tel Aviv Medical Center led by Dr. Shira Zelber-Sagi, Prof. Oren Shibolet, and Assaf Buch. The researchers decided to examine the impact of resistance training -- which is usually briefer and more focused than aerobic exercises -- on fatty liver disease. The study included 82 subjects aged 20-65 who were diagnosed by means of an ultrasound as suffering from fatty liver disease over the six months before the beginning of the study. The participants were divided randomly into a resistance training group and a control group that was asked only to undertake stretching exercises. The participants were asked not to change their physical activity habits during the study, to continue their usual diet, and to take their prescribed medicines. During the study the participants underwent examinations of weight, blood pressure, a blood test for liver enzymes, lipids, blood sugar, and insulin. Resistance training in the gym was defined according to a uniform protocol, with the level of resistance adjusted to the patient's capabilities. The training, that was desighned and delivered by Assaf Buch, included several sets of different resistance exercises involving the arms, chest, and legs and lasting for a total of 40 minutes, three times a week.

At the end of the three-month study, the researchers found that resistance training in the gym led to a decrease in liver fat based on the fat content of the liver as detected in the special ultrasound examination employed by the study. Developed by Dr. Muriel Webb, this examination enables the quantification of liver fat. Dr. Zelber-Sagi explains: "The resistance training was not intended to reduce body weight significantly, and indeed overall weight loss was very slight. However, it seems that the resistance training had a specific impact in terms of a fall in liver fat levels as measured in the ultrasound examination."

The study also found that gym training led to a significant fall in blood cholesterol levels. "We assume that the physical exercise improves the resistance to insulin, thereby reducing the production of cholesterol in the liver and its level in the blood," the researchers commented. This study also shows for the first time that resistance training led to a reduction in ferritin levels in the blood. Ferritin is a protein found in the liver that facilitates the storage of iron. However, elevated levels of ferritin can be indicative of liver damage, including inflammation. Accordingly, a fall in ferritin levels may reflect an improvement in the condition of the liver.

"We strongly recommend patients with fatty liver to get involved in routine physical activity, be it resistance training or aerobics, maintain a healthy diet and reduce weight," Prof Shibolet concludes.

Dr. Zilber-Sagi concludes "We know how hard it is for people to lose weight and to stick to weight reduction diets. Accordingly, it is important to find additional ways we can treat patients on a long-term basis while enabling them to maintain a high quality of life. Anaerobic training is one of these ways."

https://www.sciencedaily.com/releases/2015/07/150727093349.htm