健身房的阻力（力量）训练导致肝脏脂肪含量下降。这是海法大学与特拉维夫医学中心和特拉维夫大学合作的一项新研究的发现。海法大学公共卫生学院的Shira zelell - sagi博士进行了这项研究，他说:“对于那些身体受限或活动性较低的患者来说，阻止他们进行有氧运动是一种有效的选择。”
目前的研究是由海法大学的一组研究人员和由Shira Zelber-Sagi博士、Oren Shibolet教授和Assaf Buch博士领导的特拉维夫医疗中心进行的。研究人员决定研究阻力训练对脂肪肝的影响，这种训练通常比有氧运动更简单、更专注。这项研究包括82名年龄在20-65岁之间的受试者，他们在研究开始前的六个月被诊断为患有脂肪肝。参与者被随机分为一个抵抗训练组和一个被要求进行伸展运动的对照组。研究人员要求参与者在学习期间不要改变他们的身体活动习惯，继续他们的日常饮食，并服用他们的处方药。在研究期间，参与者进行了体重、血压、肝脏酶、血脂、血糖和胰岛素的血液测试。在健身房的阻力训练是根据一种统一的方案来定义的，它的阻力（力量）水平根据病人的能力而调整。这项训练是由阿萨夫·布奇设计的，包括几组不同的耐力练习，包括手臂、胸部和腿部，持续时间为40分钟，每周3次。
Good news for people suffering from fatty liver disease: Resistance training can help
July 27, 2015
University of Haifa
Approximately 30% of the population suffer from fatty liver disease, the most common liver disease in the Western world. The disease can lead to inflammation and cirrhosis of the liver. A new study has found that gym training, and not only aerobic exercises, can help reduce liver fat
Resistance training in the gym leads to a fall in liver fat levels. This is the finding of a new study held at the University of Haifa in cooperation with Tel Aviv Medical Center and Tel Aviv University. "For patients suffering from physical limitations or low motivation that prevents them performing aerobic exercises, resistance training can be an effective alternative," comments Dr. Shira Zelber-Sagi from the School of Public Health at the University of Haifa, who undertook the study.
On the basis of past studies, fatty liver disease is defined as a fat rate in excess of 5-10 percent of liver volume. The disease affects approximately 30 percent of the public and is considered the commonest liver disease in the Western world. Excessive weight, abdominal obesity, diabetes, dyslipidemia, and in particular triglycerides increase the risk of developing fatty liver disease, which can lead to inflammation and cirrhosis of the liver.
The disease is usually asymptomatic, although patients sometimes report fatigue and a lack of vitality by comparison to healthy individuals. Prof Oren Shibolet adds that "
Fatty liver causes morbidity and mortality due to metabolic complications such as diabetes and cardiovascular disease, the development of cirrhosis and liver cancer. Because drug treatment for the disease is very limited or nonexistent, the main emphasis is on life style modifications. In this aspect our study is one of a few clinical trials to show the benefit of resistance training in reducing liver fat." According to Dr. Zelber-Sagi, although patients with the disease recognize the importance of physical activity, they often lack the motivation to engage in such activity, particularly in the case of aerobic exercises, which are usually time consuming.
The current study was undertaken by a team of researchers from the University of Haifa, and the Tel Aviv Medical Center led by Dr. Shira Zelber-Sagi, Prof. Oren Shibolet, and Assaf Buch. The researchers decided to examine the impact of resistance training -- which is usually briefer and more focused than aerobic exercises -- on fatty liver disease. The study included 82 subjects aged 20-65 who were diagnosed by means of an ultrasound as suffering from fatty liver disease over the six months before the beginning of the study. The participants were divided randomly into a resistance training group and a control group that was asked only to undertake stretching exercises. The participants were asked not to change their physical activity habits during the study, to continue their usual diet, and to take their prescribed medicines. During the study the participants underwent examinations of weight, blood pressure, a blood test for liver enzymes, lipids, blood sugar, and insulin. Resistance training in the gym was defined according to a uniform protocol, with the level of resistance adjusted to the patient's capabilities. The training, that was desighned and delivered by Assaf Buch, included several sets of different resistance exercises involving the arms, chest, and legs and lasting for a total of 40 minutes, three times a week.
At the end of the three-month study, the researchers found that resistance training in the gym led to a decrease in liver fat based on the fat content of the liver as detected in the special ultrasound examination employed by the study. Developed by Dr. Muriel Webb, this examination enables the quantification of liver fat. Dr. Zelber-Sagi explains: "The resistance training was not intended to reduce body weight significantly, and indeed overall weight loss was very slight. However, it seems that the resistance training had a specific impact in terms of a fall in liver fat levels as measured in the ultrasound examination."
The study also found that gym training led to a significant fall in blood cholesterol levels. "We assume that the physical exercise improves the resistance to insulin, thereby reducing the production of cholesterol in the liver and its level in the blood," the researchers commented. This study also shows for the first time that resistance training led to a reduction in ferritin levels in the blood. Ferritin is a protein found in the liver that facilitates the storage of iron. However, elevated levels of ferritin can be indicative of liver damage, including inflammation. Accordingly, a fall in ferritin levels may reflect an improvement in the condition of the liver.
"We strongly recommend patients with fatty liver to get involved in routine physical activity, be it resistance training or aerobics, maintain a healthy diet and reduce weight," Prof Shibolet concludes.
Dr. Zilber-Sagi concludes "We know how hard it is for people to lose weight and to stick to weight reduction diets. Accordingly, it is important to find additional ways we can treat patients on a long-term basis while enabling them to maintain a high quality of life. Anaerobic training is one of these ways."